From our survey
Planning treatment rides for the first month in St. Louis
The referral came through. The insurer said yes, or at least "pending." Now someone has to work out how a person who cannot drive home after treatment gets to a clinic twice a week, and that someone is you.
This guide is for St. Louis caregivers setting up the practical side of supervised depression treatment, one step at a time through the first month. It assumes a clinician has already judged the treatment appropriate. It makes no such judgment itself, and nothing here is medical advice.
If you are still deciding where care should happen, you have company. Our commissioned survey of 443 Midwest adults found 44 percent favoring a clinic in person, with video care at home at 22 percent and a begin-in-clinic, finish-at-home sequence at 23 percent and 11 percent without a preference. The figures are final. The rest of this guide is for families who have chosen a clinic.
Step 1: Confirm what kind of site this is
Before planning a single drive, confirm what is being given. Spravato, the esketamine spray, carries FDA approval for depression that other medications did not relieve, and it may only be given at a certified site, followed by at least two hours of monitoring, with no driving until the next day. An IV ketamine clinic is a separate, off-label arrangement with its own timing. Brain Recovery Centers has a clear page on its Spravato visits that shows the kind of detail worth asking any clinic for.
Ask the front desk three things: which treatment they provide, how long a visit runs from check-in to discharge, and what they require for the ride home. Write the answers down; everything else depends on them.
Step 2: Map the actual route
In our survey, living close by was the runner-up priority, placed in the top two by 43 percent of respondents, behind insurance at 85 percent. Distance decides whether this is sustainable.
Drive the route once before the first appointment, at the hour you will really be going. Note parking, the right entrance, and whether there is somewhere to wait. A clinic in Creve Coeur is a different commitment from one in south county if you are coming from St. Charles or Edwardsville, and the Poplar Street Bridge at rush hour is another thing again.
Step 3: Build a ride roster, not a single driver
The early weeks are often the busiest. If one person does every drive, that person burns out, and a missed ride can mean a missed visit.
- List every adult who could drive at least once: a sibling, an adult child, a neighbor, a friend from church or work.
- Ask the clinic whether a rideshare home is acceptable or a named adult must pick up. Policies differ.
- Put the roster in a shared calendar with the clinic's address and phone in every entry.
- Name a backup driver for each week.
Step 4: Talk to your own employer early
If you are the main driver, the hours add up. Ask HR what family caregiving leave exists, including intermittent leave, before the third missed afternoon rather than after.
Step 5: Settle the money before the first visit
Coverage rules shape everything. Among our respondents, 65 percent called coverage decisive, or close to it, for whether they pursued this care at all, and half would accept more hoops to use insurance rather than pay themselves.
With the patient's permission, call the member number on their card and ask what they will owe per visit, whether monitoring time is billed separately, and whether the authorization covers a set number of sessions. Whether the plan is MO HealthNet, Medicare, commercial, or TRICARE, ask the clinic if it has billed that plan for this treatment before; on the Illinois side, ask the same about Illinois coverage.
Step 6: Pack a visit bag
- The insurance card, photo ID, and a current medication list.
- Water and a snack for the ride home, if the clinic allows.
- Headphones, a book, or something familiar for the patient during monitoring.
- Something for you to do, and a phone charger.
Ask the clinic whether there are instructions about eating before a visit.
Step 7: Plan the evening after
Driving is out for the patient until tomorrow, and they may feel tired or off after a session. Keep treatment days quiet: no errands on the way home, no big dinners, no decisions that can wait. Keep brief notes on how they seem that evening and the next morning; a simple log helps the clinician and helps you spot patterns.
Step 8: Keep the rest of their care connected
This treatment usually sits alongside other care, not in place of it, so the primary care doctor, any therapist, and the current prescriber should all know it has started. That matters more than it sounds. Our respondents named the primary doctor as their likely first stop 56 percent of the time, and their own doctor's word was the deciding push for 74 percent. Keep that doctor in the loop.
Step 9: Take care of the caregiver
You are not an outlier. In our survey, 72 percent reported that depression, anxiety, or PTSD standard medications did not help had touched them or someone close, and 22 percent said it was someone close rather than themselves. Many households carry what yours carries. Find your own support, whether a friend, a group, or a counselor.
When the person you look after mentions suicide, or you doubt they are safe tonight, reach 988 by call or text. The Lifeline is free and open every hour, and family members can call on someone else's behalf. In immediate danger, call 911.
Methodology
This guide's figures come from Pollfish study 395586438, a first-party survey the publisher commissioned and paid for, which closed June 23, 2026. The 443 respondents, ages 18 to 64, came from Pollfish's general consumer panel across ten Midwest states rather than any patient list. We cite top-line numbers only, with no subgroup figures; on questions allowing several answers, the percentages can pass 100. All figures come from the fully validated panel.